Welcome to the Larschan Lab at Brown University

How are global and gene-specific transcriptional regulatory signals integrated to precisely regulate genes?

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We combine genomics, genetics and computational biology to reveal new mechanisms which coordinate gene regulation across eukaryotic species.

 

TIMEOR (Trajectory Inference and Mechanism Exploration with Omics in R)

TIMEOR is the first web-based and adaptive time series multi-omics pipeline method which infers the relationship between gene regulatory events across time. TIMEOR addresses the critical need for methods to predict causal regulatory mechanism networks between TFs from time series multi-omics data.

 
 

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